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Distinct CED-10/Rac1 domains confer context-specific functions in development

Rac GTPases act as master switches to coordinate multiple interweaved signaling pathways. A major function for Rac GTPases is to control neurite development by influencing downstream effector molecules and pathways. In Caenorhabditis elegans, the Rac proteins CED-10, RAC-2 and MIG-2 act in parallel...

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Detalles Bibliográficos
Autores principales: Nørgaard, Steffen, Deng, Shuer, Cao, Wei, Pocock, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179291/
https://www.ncbi.nlm.nih.gov/pubmed/30265669
http://dx.doi.org/10.1371/journal.pgen.1007670