Autophagy proteins suppress protective type I interferon signaling in response to the murine gut microbiota

As a conserved pathway that lies at the intersection between host defense and cellular homeostasis, autophagy serves as a rheostat for immune reactions. In particular, autophagy suppresses excess type I interferon (IFN-I) production in response to viral nucleic acids. It is unknown how this function...

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Detalles Bibliográficos
Autores principales: Martin, Patricia K., Marchiando, Amanda, Xu, Ruliang, Rudensky, Eugene, Yeung, Frank, Schuster, Samantha L., Kernbauer, Elisabeth, Cadwell, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179362/
https://www.ncbi.nlm.nih.gov/pubmed/30202015
http://dx.doi.org/10.1038/s41564-018-0229-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179362/
https://www.ncbi.nlm.nih.gov/pubmed/30202015
http://dx.doi.org/10.1038/s41564-018-0229-0

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