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Autophagy proteins suppress protective type I interferon signaling in response to the murine gut microbiota

As a conserved pathway that lies at the intersection between host defense and cellular homeostasis, autophagy serves as a rheostat for immune reactions. In particular, autophagy suppresses excess type I interferon (IFN-I) production in response to viral nucleic acids. It is unknown how this function...

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Detalles Bibliográficos
Autores principales:	Martin, Patricia K., Marchiando, Amanda, Xu, Ruliang, Rudensky, Eugene, Yeung, Frank, Schuster, Samantha L., Kernbauer, Elisabeth, Cadwell, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179362/ https://www.ncbi.nlm.nih.gov/pubmed/30202015 http://dx.doi.org/10.1038/s41564-018-0229-0

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