Molecular imaging of MMP activity discriminates unstable from stable plaque phenotypes in shear-stress induced murine atherosclerosis

PURPOSE: As atherosclerotic plaque ruptures are the primary cause of ischaemic events, their preventive identification by imaging remains a clinical challenge. Matrix metalloproteinases (MMP) are involved in plaque progression and destabilisation and are therefore promising targets to characterize r...

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Detalles Bibliográficos
Autores principales: Seifert, Robert, Kuhlmann, Michael T., Eligehausen, Sarah, Kiefer, Friedemann, Hermann, Sven, Schäfers, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179381/
https://www.ncbi.nlm.nih.gov/pubmed/30304051
http://dx.doi.org/10.1371/journal.pone.0204305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179381/
https://www.ncbi.nlm.nih.gov/pubmed/30304051
http://dx.doi.org/10.1371/journal.pone.0204305

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