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Molecular imaging of MMP activity discriminates unstable from stable plaque phenotypes in shear-stress induced murine atherosclerosis
PURPOSE: As atherosclerotic plaque ruptures are the primary cause of ischaemic events, their preventive identification by imaging remains a clinical challenge. Matrix metalloproteinases (MMP) are involved in plaque progression and destabilisation and are therefore promising targets to characterize r...
Autores principales: | Seifert, Robert, Kuhlmann, Michael T., Eligehausen, Sarah, Kiefer, Friedemann, Hermann, Sven, Schäfers, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179381/ https://www.ncbi.nlm.nih.gov/pubmed/30304051 http://dx.doi.org/10.1371/journal.pone.0204305 |
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