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T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection

Coordinated production of IFN-γ by innate and adaptive immune cells is central for host defense, but can also trigger immunopathology. The investigation of the lymphoid cell-specific contribution to the IFN-γ-mediated intestinal pathology during Toxoplasma gondii infection identified CD4+ T cells as...

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Detalles Bibliográficos
Autores principales: López-Yglesias, Américo H., Burger, Elise, Araujo, Alessandra, Martin, Andrew T., Yarovinsky, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179443/
https://www.ncbi.nlm.nih.gov/pubmed/29297501
http://dx.doi.org/10.1038/mi.2017.102