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POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication

Maintenance of epigenetic integrity relies on coordinated recycling and partitioning of parental histones and deposition of newly synthesized histones during DNA replication. This process depends upon a poorly characterized network of histone chaperones, remodelers, and binding proteins. Here we imp...

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Detalles Bibliográficos
Autores principales: Bellelli, Roberto, Belan, Ondrej, Pye, Valerie E., Clement, Camille, Maslen, Sarah L., Skehel, J. Mark, Cherepanov, Peter, Almouzni, Genevieve, Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179962/
https://www.ncbi.nlm.nih.gov/pubmed/30217558
http://dx.doi.org/10.1016/j.molcel.2018.08.043