Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology

Genomic wide association studies identified the CACNA1C locus as genetically associated with both schizophrenia and bipolar affective disorder. CACNA1C encodes Cav1.2, one of four subunits of L-type voltage gated calcium channels. Variation resides in non-coding regions of CACNA1C which interact wit...

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Detalles Bibliográficos
Autores principales: Billingsley, Kimberley J., Manca, Maurizio, Gianfrancesco, Olympia, Collier, David A., Sharp, Helen, Bubb, Vivien J., Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publisher B. V 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179964/
https://www.ncbi.nlm.nih.gov/pubmed/29501388
http://dx.doi.org/10.1016/j.schres.2018.02.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179964/
https://www.ncbi.nlm.nih.gov/pubmed/29501388
http://dx.doi.org/10.1016/j.schres.2018.02.036

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