Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota

Diosgenin, a natural steroidal saponin, can exert antitumor effect by regulating immune function and improving intestinal microbiota. The response to anti-PD-1 immunotherapy is associated with intestinal microbiota and effector T cells in tumor microenvironment. We hypothesize that the modulation of...

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Detalles Bibliográficos
Autores principales: Dong, Mengxue, Meng, Zhefeng, Kuerban, Kudelaidi, Qi, Feilong, Liu, Jiayang, Wei, Yuxi, Wang, Qian, Jiang, Shanshan, Feng, Meiqing, Ye, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179990/
https://www.ncbi.nlm.nih.gov/pubmed/30305604
http://dx.doi.org/10.1038/s41419-018-1099-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179990/
https://www.ncbi.nlm.nih.gov/pubmed/30305604
http://dx.doi.org/10.1038/s41419-018-1099-3

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