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BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways

Current therapeutic options for intrahepatic cholangiocarcinoma (ICC) are very limited, which is largely attributed to poor understanding of molecular pathogenesis of ICC. Breast cancer type 1 susceptibility protein-associated protein-1 (BAP1) has been reported to be a broad-spectrum tumor suppresso...

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Detalles Bibliográficos
Autores principales: Chen, Xu-Xiao, Yin, Yue, Cheng, Jian-Wen, Huang, Ao, Hu, Bo, Zhang, Xin, Sun, Yun-Fan, Wang, Jian, Wang, Yu-Peng, Ji, Yuan, Qiu, Shuang-Jian, Fan, Jia, Zhou, Jian, Yang, Xin-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179995/
https://www.ncbi.nlm.nih.gov/pubmed/30305612
http://dx.doi.org/10.1038/s41419-018-1087-7