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GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

Gamma-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the brain; however, the roles of GABA in antimicrobial host defenses are largely unknown. Here we demonstrate that GABAergic activation enhances antimicrobial responses against intracellular bacterial infection. Intracell...

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Detalles Bibliográficos
Autores principales: Kim, Jin Kyung, Kim, Yi Sak, Lee, Hye-Mi, Jin, Hyo Sun, Neupane, Chiranjivi, Kim, Sup, Lee, Sang-Hee, Min, Jung-Joon, Sasai, Miwa, Jeong, Jae-Ho, Choe, Seong-Kyu, Kim, Jin-Man, Yamamoto, Masahiro, Choy, Hyon E., Park, Jin Bong, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180030/
https://www.ncbi.nlm.nih.gov/pubmed/30305619
http://dx.doi.org/10.1038/s41467-018-06487-5