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Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination

The DNA-damage repair pathway homologous recombination (HR) requires factors that promote the activity of strand-exchange protein RAD51 and its meiosis-specific homolog DMC1. Here we show that the Shu complex SWS1-SWSAP1, a candidate for one such HR regulator, is dispensable for mouse viability but...

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Detalles Bibliográficos
Autores principales: Abreu, Carla M., Prakash, Rohit, Romanienko, Peter J., Roig, Ignasi, Keeney, Scott, Jasin, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180034/
https://www.ncbi.nlm.nih.gov/pubmed/30305635
http://dx.doi.org/10.1038/s41467-018-06384-x