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MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes

Mitochondria are critical in heat generation in brown and beige adipocytes. Mitochondrial number and function are regulated in response to external stimuli, such as cold exposure and β3 adrenergic receptor agonist. However, the molecular mechanisms regulating mitochondrial biogenesis during browning...

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Detalles Bibliográficos
Autores principales: Lemecha, Mengistu, Morino, Katsutaro, Imamura, Takeshi, Iwasaki, Hirotaka, Ohashi, Natsuko, Ida, Shogo, Sato, Daisuke, Sekine, Osamu, Ugi, Satoshi, Maegawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180067/
https://www.ncbi.nlm.nih.gov/pubmed/30305668
http://dx.doi.org/10.1038/s41598-018-33438-3