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MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes
Mitochondria are critical in heat generation in brown and beige adipocytes. Mitochondrial number and function are regulated in response to external stimuli, such as cold exposure and β3 adrenergic receptor agonist. However, the molecular mechanisms regulating mitochondrial biogenesis during browning...
Autores principales: | Lemecha, Mengistu, Morino, Katsutaro, Imamura, Takeshi, Iwasaki, Hirotaka, Ohashi, Natsuko, Ida, Shogo, Sato, Daisuke, Sekine, Osamu, Ugi, Satoshi, Maegawa, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180067/ https://www.ncbi.nlm.nih.gov/pubmed/30305668 http://dx.doi.org/10.1038/s41598-018-33438-3 |
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