MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging

Aging is a prominent risk factor for neurodegenerative disease. Defining gene expression mechanisms affecting healthy brain aging should lead to insight into genes that modulate susceptibility to disease. To define such mechanisms, we have pursued analysis of miR-34 mutants in Drosophila. The miR-34...

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Detalles Bibliográficos
Autores principales: Kennerdell, Jason R., Liu, Nan, Bonini, Nancy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180074/
https://www.ncbi.nlm.nih.gov/pubmed/30305625
http://dx.doi.org/10.1038/s41467-018-06592-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180074/
https://www.ncbi.nlm.nih.gov/pubmed/30305625
http://dx.doi.org/10.1038/s41467-018-06592-5

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