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MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging
Aging is a prominent risk factor for neurodegenerative disease. Defining gene expression mechanisms affecting healthy brain aging should lead to insight into genes that modulate susceptibility to disease. To define such mechanisms, we have pursued analysis of miR-34 mutants in Drosophila. The miR-34...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180074/ https://www.ncbi.nlm.nih.gov/pubmed/30305625 http://dx.doi.org/10.1038/s41467-018-06592-5 |