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Biomechanics show stem cell necessity for effective treatment of volumetric muscle loss using bioengineered constructs

Despite the regenerative capacity of muscle, tissue volume is not restored after volumetric muscle loss (VML), perhaps due to a loss-of-structural extracellular matrix. We recently demonstrated the structural and functional restoration of muscle tissue in a mouse model of VML using an engineered “bi...

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Detalles Bibliográficos
Autores principales: Quarta, Marco, Cromie Lear, Melinda J., Blonigan, Justin, Paine, Patrick, Chacon, Robert, Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180087/
https://www.ncbi.nlm.nih.gov/pubmed/30323949
http://dx.doi.org/10.1038/s41536-018-0057-0