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Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI

Proteasome inhibitors (PIs) are now standard of care for several cancers, and noninvasive biomarkers of treatment response are critically required for early patient stratification and treatment personalization. The present study evaluated whether chemical exchange (CEST) magnetic resonance imaging (...

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Detalles Bibliográficos
Autores principales: Zhu, Yanan, Ramasawmy, Rajiv, Johnson, Sean Peter, Taylor, Valerie, Gibb, Alasdair, Pedley, R. Barbara, Chattopadhyay, Nibedita, Lythgoe, Mark F., Golay, Xavier, Bradley, Daniel, Walker-Samuel, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180115/
https://www.ncbi.nlm.nih.gov/pubmed/30305717
http://dx.doi.org/10.1038/s41598-018-33549-x