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Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI
Proteasome inhibitors (PIs) are now standard of care for several cancers, and noninvasive biomarkers of treatment response are critically required for early patient stratification and treatment personalization. The present study evaluated whether chemical exchange (CEST) magnetic resonance imaging (...
Autores principales: | Zhu, Yanan, Ramasawmy, Rajiv, Johnson, Sean Peter, Taylor, Valerie, Gibb, Alasdair, Pedley, R. Barbara, Chattopadhyay, Nibedita, Lythgoe, Mark F., Golay, Xavier, Bradley, Daniel, Walker-Samuel, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180115/ https://www.ncbi.nlm.nih.gov/pubmed/30305717 http://dx.doi.org/10.1038/s41598-018-33549-x |
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