Increasing G9a automethylation sensitizes B acute lymphoblastic leukemia cells to glucocorticoid-induced death

Synthetic glucocorticoids (GCs) are used to treat lymphoid cancers, but many patients develop resistance to treatment, especially to GC. By identifying genes that influence sensitivity to GC-induced cell death, we found that histone methyltransferases G9a and G9a-like protein (GLP), two glucocortico...

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Detalles Bibliográficos
Autores principales: Poulard, Coralie, Baulu, Estelle, Lee, Brian H., Pufall, Miles A., Stallcup, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180122/
https://www.ncbi.nlm.nih.gov/pubmed/30305606
http://dx.doi.org/10.1038/s41419-018-1110-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180122/
https://www.ncbi.nlm.nih.gov/pubmed/30305606
http://dx.doi.org/10.1038/s41419-018-1110-z

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