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Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery

Roux-en-Y Gastric Bypass Surgery (RYGB) prevents the occurrence of pancreatic cell acinar carcinoma (ACC) in male and female Ngn3-Tsc1−/− mice. Ngn3 directed Cre deletion of Tsc1 gene induced the development of pancreatic ACC. The transgenic mice with sham surgery demonstrated a cancer incidence of...

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Detalles Bibliográficos
Autores principales: He, Rui, Yin, Yue, Yin, Wenzhen, Li, Yin, Zhao, Jing, Zhang, Weizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180124/
https://www.ncbi.nlm.nih.gov/pubmed/30305629
http://dx.doi.org/10.1038/s41467-018-06571-w