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Causality Analysis and Cell Network Modeling of Spatial Calcium Signaling Patterns in Liver Lobules

Dynamics as well as localization of Ca(2+) transients plays a vital role in liver function under homeostatic conditions, repair, and disease. In response to circulating hormonal stimuli, hepatocytes exhibit intracellular Ca(2+) responses that propagate through liver lobules in a wave-like fashion. A...

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Detalles Bibliográficos
Autores principales: Verma, Aalap, Antony, Anil Noronha, Ogunnaike, Babatunde A., Hoek, Jan B., Vadigepalli, Rajanikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180170/
https://www.ncbi.nlm.nih.gov/pubmed/30337879
http://dx.doi.org/10.3389/fphys.2018.01377