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Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls
Aberrant, misfolded, and mislocalized proteins are often toxic to cells and result in many human diseases. All proteins and their mRNA templates are subject to quality control. There are several distinct mechanisms that control the quality of mRNAs and proteins during translation at the ribosome. mR...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180196/ https://www.ncbi.nlm.nih.gov/pubmed/30337940 http://dx.doi.org/10.3389/fgene.2018.00431 |