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Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls

Aberrant, misfolded, and mislocalized proteins are often toxic to cells and result in many human diseases. All proteins and their mRNA templates are subject to quality control. There are several distinct mechanisms that control the quality of mRNAs and proteins during translation at the ribosome. mR...

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Detalles Bibliográficos
Autores principales: Karamyshev, Andrey L., Karamysheva, Zemfira N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180196/
https://www.ncbi.nlm.nih.gov/pubmed/30337940
http://dx.doi.org/10.3389/fgene.2018.00431

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