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Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program

Epithelial‐to‐mesenchymal transition (EMT) is a recognized eukaryotic cell differentiation program that is also observed in association with invasive tumors. Partial EMT program in carcinomas imparts cancer cells with mesenchymal‐like features and is proposed as essential for metastasis. Precise det...

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Detalles Bibliográficos
Autores principales: Chen, Yang, LeBleu, Valerie S, Carstens, Julienne L, Sugimoto, Hikaru, Zheng, Xiaofeng, Malasi, Shruti, Saur, Dieter, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180301/
https://www.ncbi.nlm.nih.gov/pubmed/30120146
http://dx.doi.org/10.15252/emmm.201809085