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Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations

Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in the regulatory networks of endothelial cells that must be comprehensively understood...

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Detalles Bibliográficos
Autores principales: Otten, Cécile, Knox, Jessica, Boulday, Gwénola, Eymery, Mathias, Haniszewski, Marta, Neuenschwander, Martin, Radetzki, Silke, Vogt, Ingo, Hähn, Kristina, De Luca, Coralie, Cardoso, Cécile, Hamad, Sabri, Igual Gil, Carla, Roy, Peter, Albiges‐Rizo, Corinne, Faurobert, Eva, von Kries, Jens P, Campillos, Mónica, Tournier‐Lasserve, Elisabeth, Derry, W Brent, Abdelilah‐Seyfried, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180302/
https://www.ncbi.nlm.nih.gov/pubmed/30181117
http://dx.doi.org/10.15252/emmm.201809155