Cargando…

Selective depletion of metastatic stem cells as therapy for human colorectal cancer

Selective elimination of metastatic stem cells (MetSCs) promises to block metastatic dissemination. Colorectal cancer (CRC) cells overexpressing CXCR4 display trafficking functions and metastasis‐initiating capacity. We assessed the antimetastatic activity of a nanoconjugate (T22‐GFP‐H6‐FdU) that se...

Descripción completa

Detalles Bibliográficos
Autores principales: Céspedes, María Virtudes, Unzueta, Ugutz, Aviñó, Anna, Gallardo, Alberto, Álamo, Patricia, Sala, Rita, Sánchez‐Chardi, Alejandro, Casanova, Isolda, Mangues, María Antònia, Lopez‐Pousa, Antonio, Eritja, Ramón, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180303/
https://www.ncbi.nlm.nih.gov/pubmed/30190334
http://dx.doi.org/10.15252/emmm.201708772