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Oxidative dehalogenation and denitration by a flavin-dependent monooxygenase is controlled by substrate deprotonation

Enzymes that are capable of detoxifying halogenated phenols (HPs) and nitrophenols (NPs) are valuable for bioremediation and waste biorefining. HadA monooxygenase was found to perform dual functions of oxidative dehalogenation (hydroxylation plus halide elimination) and denitration (hydroxylation pl...

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Detalles Bibliográficos
Autores principales: Pimviriyakul, Panu, Surawatanawong, Panida, Chaiyen, Pimchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180312/
https://www.ncbi.nlm.nih.gov/pubmed/30319747
http://dx.doi.org/10.1039/c8sc01482e