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Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis

Tuberculosis claims >1 million lives annually, and its causative agent Mycobacterium tuberculosis is a highly successful pathogen. Protein kinase B (PknB) is reported to be critical for mycobacterial growth. Here, we demonstrate that PknB-depleted M. tuberculosis can replicate normally and can sy...

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Detalles Bibliográficos
Autores principales: Turapov, Obolbek, Forti, Francesca, Kadhim, Baleegh, Ghisotti, Daniela, Sassine, Jad, Straatman-Iwanowska, Anna, Bottrill, Andrew R., Moynihan, Patrick J., Wallis, Russell, Barthe, Philippe, Cohen-Gonsaud, Martin, Ajuh, Paul, Vollmer, Waldemar, Mukamolova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180346/
https://www.ncbi.nlm.nih.gov/pubmed/30282038
http://dx.doi.org/10.1016/j.celrep.2018.09.004