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Magnolol dimer-derived fragments as PPARγ-selective probes

Partial agonists of the transcription factor PPARγ (peroxisome proliferator-activated receptor γ) have shown potential for the treatment of metabolic and inflammatory conditions and novel activators serve as valuable tool and lead compounds. Based on the natural product magnolol (I) and recent struc...

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Detalles Bibliográficos
Autores principales: Dreier, Dominik, Resetar, Mirta, Temml, Veronika, Rycek, Lukas, Kratena, Nicolas, Schnürch, Michael, Schuster, Daniela, Dirsch, Verena M., Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180429/
https://www.ncbi.nlm.nih.gov/pubmed/30232493
http://dx.doi.org/10.1039/c8ob01745j