Genome-wide analysis of fitness data and its application to improve metabolic models

BACKGROUND: Synthetic biology and related techniques enable genome scale high-throughput investigation of the effect on organism fitness of different gene knock-downs/outs and of other modifications of genomic sequence. RESULTS: We develop statistical and computational pipelines and frameworks for a...

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Detalles Bibliográficos
Autores principales: Vitkin, Edward, Solomon, Oz, Sultan, Sharon, Yakhini, Zohar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180484/
https://www.ncbi.nlm.nih.gov/pubmed/30305012
http://dx.doi.org/10.1186/s12859-018-2341-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180484/
https://www.ncbi.nlm.nih.gov/pubmed/30305012
http://dx.doi.org/10.1186/s12859-018-2341-9

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