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Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination

Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3′ end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the underlying termination mechanism is not yet understood. Here, we demonstrate that the conserved and essential termination...

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Detalles Bibliográficos
Autores principales: Kecman, Tea, Kuś, Krzysztof, Heo, Dong-Hyuk, Duckett, Katie, Birot, Adrien, Liberatori, Sabrina, Mohammed, Shabaz, Geis-Asteggiante, Lucia, Robinson, Carol V., Vasiljeva, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180485/
https://www.ncbi.nlm.nih.gov/pubmed/30282034
http://dx.doi.org/10.1016/j.celrep.2018.09.007