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Efficient CRISPR–Cas9 mediated multiplex genome editing in yeasts
BACKGROUND: The thermotolerant methylotrophic yeast Ogataea polymorpha has been regarded as an important organism for basic research and biotechnological applications. It is generally recognized as an efficient and safe cell factory in fermentative productions of chemicals, biofuels and other bio-pr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180501/ https://www.ncbi.nlm.nih.gov/pubmed/30337956 http://dx.doi.org/10.1186/s13068-018-1271-0 |