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R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells
BACKGROUND: As newly identified Wnt enhancer, R-spondin gene family members have been linked to various cancers; however, their role in isocitrate dehydrogenase-wildtype subtype of human glioblastoma (GBM) cells remains unknown. METHODS: Human U87 and U251 cell lines were used to perform the experim...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180579/ https://www.ncbi.nlm.nih.gov/pubmed/30337838 http://dx.doi.org/10.1186/s12935-018-0655-3 |