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R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells

BACKGROUND: As newly identified Wnt enhancer, R-spondin gene family members have been linked to various cancers; however, their role in isocitrate dehydrogenase-wildtype subtype of human glioblastoma (GBM) cells remains unknown. METHODS: Human U87 and U251 cell lines were used to perform the experim...

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Detalles Bibliográficos
Autores principales:	Liu, Si, U, Kin Pong, Zhang, Jieting, Tsang, Lai Ling, Huang, Jiawei, Tu, Shui Ping, Jiang, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180579/ https://www.ncbi.nlm.nih.gov/pubmed/30337838 http://dx.doi.org/10.1186/s12935-018-0655-3

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