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Thirty biologically interpretable clusters of transcription factors distinguish cancer type

BACKGROUND: Transcription factors are essential regulators of gene expression and play critical roles in development, differentiation, and in many cancers. To carry out their regulatory programs, they must cooperate in networks and bind simultaneously to sites in promoter or enhancer regions of gene...

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Detalles Bibliográficos
Autores principales: Abrams, Zachary B., Zucker, Mark, Wang, Min, Asiaee Taheri, Amir, Abruzzo, Lynne V., Coombes, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180590/
https://www.ncbi.nlm.nih.gov/pubmed/30305013
http://dx.doi.org/10.1186/s12864-018-5093-z