A lipidated bi-epitope vaccine comprising of MHC-I and MHC-II binder peptides elicits protective CD4 T cell and CD8 T cell immunity against Mycobacterium tuberculosis

BACKGROUND: The clinical trials conducted at Chingleput India suggest that BCG fails to protect against tuberculosis (TB) in TB-endemic population. Recent studies advocate that non-tuberculous mycobacteria and latent Mycobacterium tuberculosis (Mtb) infection interferes in the antigen processing and...

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Detalles Bibliográficos
Autores principales: Rai, Pradeep K., Chodisetti, Sathi Babu, Maurya, Sudeep K., Nadeem, Sajid, Zeng, Weiguang, Janmeja, Ashok K., Jackson, David C., Agrewala, Javed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180631/
https://www.ncbi.nlm.nih.gov/pubmed/30305097
http://dx.doi.org/10.1186/s12967-018-1653-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180631/
https://www.ncbi.nlm.nih.gov/pubmed/30305097
http://dx.doi.org/10.1186/s12967-018-1653-x

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