Cantharidin Inhibits Anti-Apoptotic Bcl-2 Family Proteins and Induces Apoptosis in Human Osteosarcoma Cell Lines MG-63 and MNNG/HOS via Mitochondria-Dependent Pathway

BACKGROUND: Cantharidin (CTD) is one of the major active ingredients of blister beetles and has significant antitumor activity in many cancer cell lines. The aim of our study was to evaluate the effect of CTD on the apoptosis of human osteosarcoma cells MG-63 and MNNG/HOS, and to explore the possibl...

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Detalles Bibliográficos
Autores principales: Feng, Shoumin, Zhu, Jian, Xia, Kaishun, Yu, Wei, Wang, Yitian, Wang, Junjie, Li, Fangcai, Yang, Zhengming, Yang, Xiaobo, Liu, Bing, Tao, Huimin, Liang, Chengzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180936/
https://www.ncbi.nlm.nih.gov/pubmed/30248086
http://dx.doi.org/10.12659/MSM.910294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180936/
https://www.ncbi.nlm.nih.gov/pubmed/30248086
http://dx.doi.org/10.12659/MSM.910294

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