α-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-κB Signaling in Colon Cancer Cells

Colon cancer represents the third most common malignancy worldwide. New drugs with high efficaciousness and safety for the treatment of colon cancer are urgently needed in clinical context. Here, we were aimed to evaluate the antitumor activity of the natural compound α-hederin in human colon cancer...

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Detalles Bibliográficos
Autores principales: Sun, Dongdong, Shen, Weixing, Zhang, Feng, Fan, Huisen, Tan, Jiani, Li, Liu, Xu, Changliang, Zhang, Haibin, Yang, Ye, Cheng, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180961/
https://www.ncbi.nlm.nih.gov/pubmed/30363706
http://dx.doi.org/10.1155/2018/2548378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180961/
https://www.ncbi.nlm.nih.gov/pubmed/30363706
http://dx.doi.org/10.1155/2018/2548378

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