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Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy

PURPOSE: Oxidative stress plays a central role in the development of diabetic retinopathy, and in the pathogenesis of this blinding disease, activation of NADPH oxidase 2 (Nox2)-mediated cytosolic reactive oxygen species (ROS) production precedes mitochondrial damage. The multicomponent cytosolic No...

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Detalles Bibliográficos
Autores principales: Duraisamy, Arul J., Mishra, Manish, Kowluru, Anjaneyulu, Kowluru, Renu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181189/
https://www.ncbi.nlm.nih.gov/pubmed/30347077
http://dx.doi.org/10.1167/iovs.18-24548