Cargando…

Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy

PURPOSE: Oxidative stress plays a central role in the development of diabetic retinopathy, and in the pathogenesis of this blinding disease, activation of NADPH oxidase 2 (Nox2)-mediated cytosolic reactive oxygen species (ROS) production precedes mitochondrial damage. The multicomponent cytosolic No...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duraisamy, Arul J., Mishra, Manish, Kowluru, Anjaneyulu, Kowluru, Renu A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181189/ https://www.ncbi.nlm.nih.gov/pubmed/30347077 http://dx.doi.org/10.1167/iovs.18-24548

Ejemplares similares

Crosstalk Between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in Diabetes
por: Duraisamy, Arul J., et al.
Publicado: (2017)

The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy
por: Mishra, Manish, et al.
Publicado: (2016)

Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy
por: Mohammad, Ghulam, et al.
Publicado: (2019)

Peripheral Blood Mitochondrial DNA Damage as a Potential Noninvasive Biomarker of Diabetic Retinopathy
por: Mishra, Manish, et al.
Publicado: (2016)

Hydrogen Sulfide: A Potential Therapeutic Target in the Development of Diabetic Retinopathy
por: Mohammad, Ghulam, et al.
Publicado: (2020)

Cross Talks between Oxidative Stress, Inflammation and Epigenetics in Diabetic Retinopathy
por: Kowluru, Renu A.
Publicado: (2023)

Epigenetic Modifications and Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2013)

Epigenetic Modifications in Peripheral Blood as Potential Noninvasive Biomarker of Diabetic Retinopathy
por: Duraisamy, Arul J., et al.
Publicado: (2019)

Oxidative Stress and Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2007)

Regulation of Matrix Metalloproteinase-9 by Epigenetic Modifications and the Development of Diabetic Retinopathy
por: Zhong, Qing, et al.
Publicado: (2013)

Mitochondrial Stability in Diabetic Retinopathy: Lessons Learned From Epigenetics
por: Kowluru, Renu A.
Publicado: (2019)

The Long Non-Coding RNA HOTAIR Is a Critical Epigenetic Mediator of Angiogenesis in Diabetic Retinopathy
por: Biswas, Saumik, et al.
Publicado: (2021)

Epigenetic Changes in Mitochondrial Superoxide Dismutase in the Retina and the Development of Diabetic Retinopathy
por: Zhong, Qing, et al.
Publicado: (2011)

Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation
por: Veluthakal, Rajakrishnan, et al.
Publicado: (2015)

Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2016)

Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2020)

MicroRNA 9 Is a Regulator of Endothelial to Mesenchymal Transition in Diabetic Retinopathy
por: Wang, Eric, et al.
Publicado: (2023)

Increased oxidative stress in diabetes regulates activation of a small molecular weight G-protein, H-Ras, in the retina
por: Kowluru, Vibhuti, et al.
Publicado: (2007)

Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy
por: Kim, Dongjoon, et al.
Publicado: (2020)

Oxidative Stress in Cytokine-Induced Dysfunction of the Pancreatic Beta Cell: Known Knowns and Known Unknowns
por: Kowluru, Anjaneyulu
Publicado: (2020)

Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy
por: Lessieur, Emma M., et al.
Publicado: (2021)

Diabetic Retinopathy: Mitochondria Caught in a Muddle of Homocysteine
por: Kowluru, Renu A.
Publicado: (2020)

Photoreceptor Degeneration Accompanies Vascular Changes in a Zebrafish Model of Diabetic Retinopathy
por: Ali, Zaheer, et al.
Publicado: (2020)

Long Noncoding RNAs and Mitochondrial Homeostasis in the Development of Diabetic Retinopathy
por: Kowluru, Renu A.
Publicado: (2022)

Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy
por: Song, Brian, et al.
Publicado: (2018)

The Regulatory Role of Rac1, a Small Molecular Weight GTPase, in the Development of Diabetic Retinopathy
por: Sahajpal, Nikhil, et al.
Publicado: (2019)

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy
por: McLaughlin, Todd, et al.
Publicado: (2023)

Diabetes Modulates Iodothyronine Deiodinase 2 Expression in the Mouse Retina: A Role for Thyroid Hormone in the Pathogenesis of Diabetic Retinopathy
por: Bapputty, Reena, et al.
Publicado: (2023)

Diabetic Retinopathy and NADPH Oxidase-2: A Sweet Slippery Road
por: Kowluru, Renu A.
Publicado: (2021)

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy
por: Tien, Thomas, et al.
Publicado: (2017)

Young Ossabaw Pigs Fed a Western Diet Exhibit Early Signs of Diabetic Retinopathy
por: Lim, Rayne R., et al.
Publicado: (2018)

High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy
por: Nguyen, Ngan-Ha, et al.
Publicado: (2020)

Mitochondrial Dynamics in the Metabolic Memory of Diabetic Retinopathy
por: Mohammad, Ghulam, et al.
Publicado: (2022)

Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2(Akita/+) Murine Model of Diabetic Retinopathy
por: Wang, Jing, et al.
Publicado: (2016)

Regulation of Rac1 transcription by histone and DNA methylation in diabetic retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2021)

Viral Retinopathy in Experimental Models of Zika Infection
por: Zhao, Zhenyang, et al.
Publicado: (2017)

Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy and Mitochondrial Dysfunction
por: Mohammad, Ghulam, et al.
Publicado: (2010)

Mitochondrial Fragmentation in a High Homocysteine Environment in Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2022)

Effects of curcumin on retinal oxidative stress and inflammation in diabetes
por: Kowluru, Renu A, et al.
Publicado: (2007)

Faulty homocysteine recycling in diabetic retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_40tcdj34anjbgoer1gpojlh4cq