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Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold
PURPOSE: We generated universal corneal epithelial cells (CEC) from human embryonic stem cells (hESC) by genetically removing human leukocyte antigens (HLA) class I from the cell surface. METHODS: The serum-free, growth factor-free, and defined medium E6 was used to differentiate hESC to CEC. Decell...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181193/ https://www.ncbi.nlm.nih.gov/pubmed/30323996 http://dx.doi.org/10.1167/tvst.7.5.23 |