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Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold

PURPOSE: We generated universal corneal epithelial cells (CEC) from human embryonic stem cells (hESC) by genetically removing human leukocyte antigens (HLA) class I from the cell surface. METHODS: The serum-free, growth factor-free, and defined medium E6 was used to differentiate hESC to CEC. Decell...

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Detalles Bibliográficos
Autores principales: Yang, Juan, Park, Jung Woo, Zheng, Dejin, Xu, Ren-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181193/
https://www.ncbi.nlm.nih.gov/pubmed/30323996
http://dx.doi.org/10.1167/tvst.7.5.23