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Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
Cancer cells rely on dysregulated gene expression. This establishes specific transcriptional addictions that may be therapeutically exploited. Yet, the mechanisms ultimately responsible for these addictions are poorly understood. Here we investigated the transcriptional dependencies of transformed c...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181206/ https://www.ncbi.nlm.nih.gov/pubmed/30224758 http://dx.doi.org/10.1038/s41591-018-0158-8 |