Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH‐dependent

Cellular engineering approaches have been proposed to mitigate unintended proteolysis in plant protein biofactories, involving the design of protease activity‐depleted environments by gene silencing or in situ inactivation with accessory protease inhibitors. Here, we assessed the impact of influenza...

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Detalles Bibliográficos
Autores principales: Jutras, Philippe V., Goulet, Marie‐Claire, Lavoie, Pierre‐Olivier, D'Aoust, Marc‐André, Sainsbury, Frank, Michaud, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181212/
https://www.ncbi.nlm.nih.gov/pubmed/29618167
http://dx.doi.org/10.1111/pbi.12928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181212/
https://www.ncbi.nlm.nih.gov/pubmed/29618167
http://dx.doi.org/10.1111/pbi.12928

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