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Oral-Only Linezolid-Rifampin Is Highly Effective Compared with Other Antibiotics for Periprosthetic Joint Infection: Study of a Mouse Model

BACKGROUND: The medical treatment of periprosthetic joint infection (PJI) involves prolonged systemic antibiotic courses, often with suboptimal clinical outcomes including increased morbidity and health-care costs. Oral and intravenous monotherapies and combination antibiotic regimens were evaluated...

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Detalles Bibliográficos
Autores principales: Thompson, John M., Saini, Vikram, Ashbaugh, Alyssa G., Miller, Robert J., Ordonez, Alvaro A., Ortines, Roger V., Wang, Yu, Sterling, Robert S., Jain, Sanjay K., Miller, Lloyd S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Journal of Bone and Joint Surgery, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181281/
https://www.ncbi.nlm.nih.gov/pubmed/28419033
http://dx.doi.org/10.2106/JBJS.16.01002