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Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator

Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide phosphorylase (PNPase). Although this discovery provided an important tool for deciphering the genetic code, subsequent work revealed that the...

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Detalles Bibliográficos
Autores principales: Cameron, Todd A., Matz, Lisa M., De Lay, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181284/
https://www.ncbi.nlm.nih.gov/pubmed/30307990
http://dx.doi.org/10.1371/journal.pgen.1007654