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High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans

INTRODUCTION: Pulmonary tuberculosis (TB) is a major worldwide health problem that lacks robust blood-based biomarkers for detection of active disease. High-resolution metabolomics (HRM) is an innovative method to discover low-abundance metabolites as putative blood biomarkers to detect TB disease,...

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Detalles Bibliográficos
Autores principales: Collins, Jeffrey M., Walker, Douglas I., Jones, Dean P., Tukvadze, Nestani, Liu, Ken H., Tran, ViLinh T., Uppal, Karan, Frediani, Jennifer K., Easley, Kirk A., Shenvi, Neeta, Khadka, Manoj, Ortlund, Eric A., Kempker, Russell R., Blumberg, Henry M., Ziegler, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181350/
https://www.ncbi.nlm.nih.gov/pubmed/30308073
http://dx.doi.org/10.1371/journal.pone.0205398