Anti-metastatic effect of metformin via repression of interleukin 6-induced epithelial–mesenchymal transition in human colon cancer cells

Metformin, a first-line drug used to treat type 2 diabetes, has also been shown to have anticancer effects against a variety of malignancies, including colorectal cancer. Although inhibition of the mTOR pathway is known to be the most important mechanism for the antitumor effects of metformin, other...

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Detalles Bibliográficos
Autores principales: Kang, Sanghee, Kim, Bo Ram, Kang, Myoung-Hee, Kim, Dae-Young, Lee, Dae-Hee, Oh, Sang Cheul, Min, Byung Wook, Um, Jun Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181375/
https://www.ncbi.nlm.nih.gov/pubmed/30308035
http://dx.doi.org/10.1371/journal.pone.0205449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181375/
https://www.ncbi.nlm.nih.gov/pubmed/30308035
http://dx.doi.org/10.1371/journal.pone.0205449

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