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MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis

BACKGROUND: A characteristic pathology of early onset myasthenia gravis is thymic hyperplasia with ectopic germinal centers (GC). However, the mechanisms that trigger and maintain thymic hyperplasia are poorly characterized. Dysregulation of small, non-coding microRNAs (miRNAs) and their target gene...

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Detalles Bibliográficos
Autores principales: Sengupta, Manjistha, Wang, Bi-Dar, Lee, Norman H., Marx, Alexander, Kusner, Linda L., Kaminski, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181382/
https://www.ncbi.nlm.nih.gov/pubmed/30308012
http://dx.doi.org/10.1371/journal.pone.0205464