A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages

As antimicrobial signalling molecules, type III or lambda interferons (IFNλs) are critical for defence against infection by diverse pathogens, including bacteria, fungi and viruses. Counter-intuitively, expression of one member of the family, IFNλ4, is associated with decreased clearance of hepatiti...

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Detalles Bibliográficos
Autores principales: Bamford, Connor G. G., Aranday-Cortes, Elihu, Filipe, Ines Cordeiro, Sukumar, Swathi, Mair, Daniel, Filipe, Ana da Silva, Mendoza, Juan L., Garcia, K. Christopher, Fan, Shaohua, Tishkoff, Sarah A., McLauchlan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181419/
https://www.ncbi.nlm.nih.gov/pubmed/30308076
http://dx.doi.org/10.1371/journal.ppat.1007307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181419/
https://www.ncbi.nlm.nih.gov/pubmed/30308076
http://dx.doi.org/10.1371/journal.ppat.1007307

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